It's also important that you establish a clear hierarchy. To achieve the perfect contrast, you'll often want to pair a serif font with a sans serif font.

You don't often find that similar serifs or similar sans serifs look particularly nice next to each other. If typefaces are too similar, it's likely that they'll conflict. For some inexplicable reason, તરુણાવસ્થા is the only word in this book that uses this ligature, otherwise below-base style is used.Contrasting fonts can be hard to find as you're effectively searching for two fonts that are totally different but also complement each other rather than causing conflict. (From 2015) (Available here along with other textbooks.) I have typed the same word in Noto Serif Gujarati for comparison. Examples from Kalrav, a textbook for children in 1st standard (grade) published by Gujarat State Board.(Available here along with other publications.) (From 2009)

Words ગુરુ and ગુરુત્વાકર્ષણ from a Guj-Guj dictionary/thesaurus (shabdkosh) published by Directorate of Language, Gujarat.

Compare ગુરુ from Saarth Jodani Kosh above.) On the other hand, here is an example of the below-base style in a 9th standard Science textbook published by Gujarati State Board in 2014. (Note that Nirmala UI has copied both ligatures from Devanagari.) The last column is what a below-base style would look like in these fonts. However, Shruti (MS default in older versions) uses the below-base style. Nirmala UI (Microsoft’s default Indic font), Arial Unicode MS, Lohit Gujarati, and all Gujarati fonts on Google Fonts use this style. I have found some modern publications using this style. I found instances of રુ ligature in Saarth Jodanikosh which is a thesaurus and spelling reference book from 1949. I’ve gone back and checked a few examples for both cases. Almost all default Gujarati fonts have the ligature, so you’ll see a difference between રુ and ર‌ુ.) (I’m using ZWJ to break the ligatures here.

This is consistent with Gujarati rū (રૂ) which was probably derived from ર‍ૂ. However, as far as I remember, Gujarati ru is written normally with the u-matra below the letter, ર‌ુ. In both Sans and Serif Gujarati, the letter combination રુ (ru = ર + ુ) is rendered as a ligature where the u-matra is connected to the right side of the letter. र = Devanagari Ra (u+0930) (only for comparison).રૂ = ર + ૂ (u+0ac2) (Gujarati vowel sign Uu).રુ = ર + ુ (u+0ac1) (Gujarati vowel sign U).So I created this issue on Google Fonts back in September, but it is relevant here as well.

Stylish gujarati fonts